Strictly co-isogenic C57BL/6J-Prnp(−/−) mice: A rigorous resource for prion science

Although its involvement in prion replication and neurotoxicity during transmissible spongiform encephalopathies is undisputed, the physiological role of the cellular prion protein (PrP(C)) remains enigmatic. A plethora of functions have been ascribed to PrP(C) based on phenotypes of Prnp(−/−) mice....

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Detalles Bibliográficos
Autores principales: Nuvolone, Mario, Hermann, Mario, Sorce, Silvia, Russo, Giancarlo, Tiberi, Cinzia, Schwarz, Petra, Minikel, Eric, Sanoudou, Despina, Pelczar, Pawel, Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813672/
https://www.ncbi.nlm.nih.gov/pubmed/26926995
http://dx.doi.org/10.1084/jem.20151610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813672/
https://www.ncbi.nlm.nih.gov/pubmed/26926995
http://dx.doi.org/10.1084/jem.20151610

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