Cargando…
Strictly co-isogenic C57BL/6J-Prnp(−/−) mice: A rigorous resource for prion science
Although its involvement in prion replication and neurotoxicity during transmissible spongiform encephalopathies is undisputed, the physiological role of the cellular prion protein (PrP(C)) remains enigmatic. A plethora of functions have been ascribed to PrP(C) based on phenotypes of Prnp(−/−) mice....
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813672/ https://www.ncbi.nlm.nih.gov/pubmed/26926995 http://dx.doi.org/10.1084/jem.20151610 |