Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry

Small-molecule microarray (SMM) is an effective platform for identifying lead compounds from large collections of small molecules in drug discovery, and efficient immobilization of molecular compounds is a pre-requisite for the success of such a platform. On an isocyanate functionalized surface, we...

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Detalles Bibliográficos
Autores principales: Zhu, Chenggang, Zhu, Xiangdong, Landry, James P., Cui, Zhaomeng, Li, Quanfu, Dang, Yongjun, Mi, Lan, Zheng, Fengyun, Fei, Yiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813953/
https://www.ncbi.nlm.nih.gov/pubmed/26999137
http://dx.doi.org/10.3390/s16030378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813953/
https://www.ncbi.nlm.nih.gov/pubmed/26999137
http://dx.doi.org/10.3390/s16030378

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