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Developing an Efficient and General Strategy for Immobilization of Small Molecules onto Microarrays Using Isocyanate Chemistry
Small-molecule microarray (SMM) is an effective platform for identifying lead compounds from large collections of small molecules in drug discovery, and efficient immobilization of molecular compounds is a pre-requisite for the success of such a platform. On an isocyanate functionalized surface, we...
Autores principales: | Zhu, Chenggang, Zhu, Xiangdong, Landry, James P., Cui, Zhaomeng, Li, Quanfu, Dang, Yongjun, Mi, Lan, Zheng, Fengyun, Fei, Yiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813953/ https://www.ncbi.nlm.nih.gov/pubmed/26999137 http://dx.doi.org/10.3390/s16030378 |
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