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Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes

Eukaryotic cells rapidly repair wounds on their plasma membrane. Resealing is Ca(2+-)dependent, and involves exocytosis of lysosomes followed by massive endocytosis. Extracellular activity of the lysosomal enzyme acid sphingomyelinase was previously shown to promote endocytosis and wound removal. Ho...

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Detalles Bibliográficos
Autores principales: Castro-Gomes, Thiago, Corrotte, Matthias, Tam, Christina, Andrews, Norma W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814109/
https://www.ncbi.nlm.nih.gov/pubmed/27028538
http://dx.doi.org/10.1371/journal.pone.0152583