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Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications

The understanding of G-protein coupled receptors (GPCRs) is undergoing a revolution due to increased information about their signaling and the experimental determination of structures for more than 25 receptors. The availability of at least one receptor structure for each of the GPCR classes, well s...

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Detalles Bibliográficos
Autores principales: Cvicek, Vaclav, Goddard, William A., Abrol, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814114/
https://www.ncbi.nlm.nih.gov/pubmed/27028541
http://dx.doi.org/10.1371/journal.pcbi.1004805