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Somatic frameshift mutations in the Bloom syndrome BLM gene are frequent in sporadic gastric carcinomas with microsatellite mutator phenotype

BACKGROUND: Genomic instability has been reported at microsatellite tracts in few coding sequences. We have shown that the Bloom syndrome BLM gene may be a target of microsatelliteinstability (MSI) in a short poly-adenine repeat located in its coding region. To further characterize the involvement o...

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Detalles Bibliográficos
Autores principales: Calin, George, Ranzani, Guglielmina N, Amadori, Dino, Herlea, Vlad, Matei, Irina, Barbanti-Brodano, Giuseppe, Negrini, Massimo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC48142/
https://www.ncbi.nlm.nih.gov/pubmed/11532193
http://dx.doi.org/10.1186/1471-2156-2-14