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Protection of scaffold protein Isu from degradation by the Lon protease Pim1 as a component of Fe–S cluster biogenesis regulation

Iron–sulfur (Fe–S) clusters, essential protein cofactors, are assembled on the mitochondrial scaffold protein Isu and then transferred to recipient proteins via a multistep process in which Isu interacts sequentially with multiple protein factors. This pathway is in part regulated posttranslationall...

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Detalles Bibliográficos
Autores principales: Ciesielski, Szymon J., Schilke, Brenda, Marszalek, Jaroslaw, Craig, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814215/
https://www.ncbi.nlm.nih.gov/pubmed/26842892
http://dx.doi.org/10.1091/mbc.E15-12-0815