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Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion

The apical brush border membrane (BBM) of intestinal epithelial cells forms a highly structured and dynamic environmental interface that serves to regulate cellular physiology and block invasion by intestinal microbes and their products. How the BBM dynamically responds to pathogenic and commensal b...

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Detalles Bibliográficos
Autores principales: Saslowsky, David E., Thiagarajah, Jay R., McCormick, Beth A., Lee, Jean C., Lencer, Wayne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814219/
https://www.ncbi.nlm.nih.gov/pubmed/26864627
http://dx.doi.org/10.1091/mbc.E15-05-0293