Cargando…

How the kinetochore couples microtubule force and centromere stretch to move chromosomes

The Ndc80 complex (Ndc80, Nuf2, Spc24, Spc25) is a highly conserved kinetochore protein essential for end-on anchorage to spindle microtubule plus-ends and for force generation coupled to plus-end polymerization and depolymerization. Spc24/Spc25 at one end of the Ndc80 complex binds the kinetochore....

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Aussie, Badger, Benjamin L., Haase, Julian, Ohashi, Tomoo, Erickson, Harold P., Salmon, Edward D., Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814359/
https://www.ncbi.nlm.nih.gov/pubmed/26974660
http://dx.doi.org/10.1038/ncb3323