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Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery123

Brain-derived neurotrophic factor (BDNF) levels are elevated after status epilepticus (SE), leading to activation of multiple signaling pathways, including the janus kinase/signal transducer and activator of transcription pathway that mediates a decrease in GABA(A) receptor α1 subunits in the hippoc...

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Detalles Bibliográficos
Autores principales: Thomas, Ajay X., Cruz Del Angel, Yasmin, Gonzalez, Marco I., Carrel, Andrew J., Carlsen, Jessica, Lam, Philip M., Hempstead, Barbara L., Russek, Shelley. J., Brooks-Kayal, Amy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814566/
https://www.ncbi.nlm.nih.gov/pubmed/27057559
http://dx.doi.org/10.1523/ENEURO.0020-15.2016