Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design

Palladium-catalysed C(sp(2))–N cross-coupling (that is, Buchwald–Hartwig amination) is employed widely in synthetic chemistry, including in the pharmaceutical industry, for the synthesis of (hetero)aniline derivatives. However, the cost and relative scarcity of palladium provides motivation for the...

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Detalles Bibliográficos
Autores principales: Lavoie, Christopher M., MacQueen, Preston M., Rotta-Loria, Nicolas L., Sawatzky, Ryan S., Borzenko, Andrey, Chisholm, Alicia J., Hargreaves, Breanna K. V., McDonald, Robert, Ferguson, Michael J., Stradiotto, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814586/
https://www.ncbi.nlm.nih.gov/pubmed/27004442
http://dx.doi.org/10.1038/ncomms11073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814586/
https://www.ncbi.nlm.nih.gov/pubmed/27004442
http://dx.doi.org/10.1038/ncomms11073

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