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Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design
Palladium-catalysed C(sp(2))–N cross-coupling (that is, Buchwald–Hartwig amination) is employed widely in synthetic chemistry, including in the pharmaceutical industry, for the synthesis of (hetero)aniline derivatives. However, the cost and relative scarcity of palladium provides motivation for the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814586/ https://www.ncbi.nlm.nih.gov/pubmed/27004442 http://dx.doi.org/10.1038/ncomms11073 |