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Oncogenic Intra-p53 Family Member Interactions in Human Cancers

The p53 gene family members p53, p73, and p63 display several isoforms derived from the presence of internal promoters and alternative splicing events. They are structural homologs but hold peculiar functional properties. p53, p73, and p63 are tumor suppressor genes that promote differentiation, sen...

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Detalles Bibliográficos
Autores principales: Ferraiuolo, Maria, Di Agostino, Silvia, Blandino, Giovanni, Strano, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814729/
https://www.ncbi.nlm.nih.gov/pubmed/27066457
http://dx.doi.org/10.3389/fonc.2016.00077