Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation

Bone morphogenetic proteins (BMPs) regulate hard tissue formation, including bone and tooth. Growth differentiation factor 5 (GDF5), a known BMP, is expressed in cartilage and regulates chondrogenesis, and mutations have been shown to cause osteoarthritis. Notably, GDF5 is also expressed in periodon...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jia, Saito, Kan, Maruya, Yuriko, Nakamura, Takashi, Yamada, Aya, Fukumoto, Emiko, Ishikawa, Momoko, Iwamoto, Tsutomu, Miyazaki, Kanako, Yoshizaki, Keigo, Ge, Lihong, Fukumoto, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814822/
https://www.ncbi.nlm.nih.gov/pubmed/27030100
http://dx.doi.org/10.1038/srep23670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814822/
https://www.ncbi.nlm.nih.gov/pubmed/27030100
http://dx.doi.org/10.1038/srep23670

Ejemplares similares