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Bioengineering of Tobacco Mosaic Virus to Create a Non-Infectious Positive Control for Ebola Diagnostic Assays

The 2014 Ebola epidemic is the largest to date. There is no cure or treatment for this deadly disease; therefore there is an urgent need to develop new diagnostics to accurately detect Ebola. Current RT-PCR assays lack sensitive and reliable positive controls. To address this critical need, we devis...

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Detalles Bibliográficos
Autores principales: Lam, Patricia, Gulati, Neetu M., Stewart, Phoebe L., Keri, Ruth A., Steinmetz, Nicole F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814824/
https://www.ncbi.nlm.nih.gov/pubmed/27030058
http://dx.doi.org/10.1038/srep23803