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Sex-Related Differences of Lipid Metabolism Induced by Triptolide: The Possible Role of the LXRα/SREBP-1 Signaling Pathway

Triptolide, a diterpenoid isolated from the plant Tripterygium wilfordii Hook. f., exerts a unique bioactive spectrum of anti-inflammatory and anticancer activities. However, triptolide’s clinical applications are limited due to its severe toxicities. Fatty liver toxicity occurs in response to tript...

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Detalles Bibliográficos
Autores principales: Jiang, Zhenzhou, Huang, Xiao, Huang, Shan, Guo, Hongli, Wang, Lu, Li, Xiaojiaoyang, Huang, Xin, Wang, Tao, Zhang, Luyong, Sun, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814849/
https://www.ncbi.nlm.nih.gov/pubmed/27065871
http://dx.doi.org/10.3389/fphar.2016.00087