Cargando…

Role of Rho kinase and Na(+)/H(+) exchange in hypoxia‐induced pulmonary arterial smooth muscle cell proliferation and migration

Abnormal proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) are hallmark characteristics of vascular remodeling in pulmonary hypertension induced by chronic hypoxia. In this study, we investigated the role of the Na(+)/H(+) exchanger (NHE) and alterations in intracellular...

Descripción completa

Detalles Bibliográficos
Autores principales: Walker, Jasmine, Undem, Clark, Yun, Xin, Lade, Julie, Jiang, Haiyang, Shimoda, Larissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814889/
https://www.ncbi.nlm.nih.gov/pubmed/27009277
http://dx.doi.org/10.14814/phy2.12702