Prioritization of anticancer drugs against a cancer using genomic features of cancer cells: A step towards personalized medicine

In this study, we investigated drug profile of 24 anticancer drugs tested against a large number of cell lines in order to understand the relation between drug resistance and altered genomic features of a cancer cell line. We detected frequent mutations, high expression and high copy number variatio...

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Detalles Bibliográficos
Autores principales: Gupta, Sudheer, Chaudhary, Kumardeep, Kumar, Rahul, Gautam, Ankur, Nanda, Jagpreet Singh, Dhanda, Sandeep Kumar, Brahmachari, Samir Kumar, Raghava, Gajendra P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814902/
https://www.ncbi.nlm.nih.gov/pubmed/27030518
http://dx.doi.org/10.1038/srep23857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814902/
https://www.ncbi.nlm.nih.gov/pubmed/27030518
http://dx.doi.org/10.1038/srep23857

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