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Prioritization of anticancer drugs against a cancer using genomic features of cancer cells: A step towards personalized medicine
In this study, we investigated drug profile of 24 anticancer drugs tested against a large number of cell lines in order to understand the relation between drug resistance and altered genomic features of a cancer cell line. We detected frequent mutations, high expression and high copy number variatio...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814902/ https://www.ncbi.nlm.nih.gov/pubmed/27030518 http://dx.doi.org/10.1038/srep23857 |