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Icariin attenuates titanium-particle inhibition of bone formation by activating the Wnt/β-catenin signaling pathway in vivo and in vitro

Wear-debris-induced periprosthetic osteolysis (PIO) is a common clinical condition following total joint arthroplasty, which can cause implant instability and failure. The host response to wear debris promotes bone resorption and impairs bone formation. We previously demonstrated that icariin suppre...

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Detalles Bibliográficos
Autores principales: Wang, Junhua, Tao, Yunxia, Ping, Zichuan, Zhang, Wen, Hu, Xuanyang, Wang, Yijun, Wang, Liangliang, Shi, Jiawei, Wu, Xiexing, Yang, Huilin, Xu, Yaozeng, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814911/
https://www.ncbi.nlm.nih.gov/pubmed/27029606
http://dx.doi.org/10.1038/srep23827