β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H

CREB-H is an endoplasmic reticulum-resident bZIP transcription factor which critically regulates lipid homeostasis and gluconeogenesis in the liver. CREB-H is proteolytically activated by regulated intramembrane proteolysis to generate a C-terminally truncated form known as CREB-H-ΔTC, which translo...

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Detalles Bibliográficos
Autores principales: Cheng, Yun, Gao, Wei-Wei, Tang, Hei-Man Vincent, Deng, Jian-Jun, Wong, Chi-Ming, Chan, Chi-Ping, Jin, Dong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814919/
https://www.ncbi.nlm.nih.gov/pubmed/27029215
http://dx.doi.org/10.1038/srep23938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814919/
https://www.ncbi.nlm.nih.gov/pubmed/27029215
http://dx.doi.org/10.1038/srep23938

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