KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathways

Autophagy is emerging as an important pathway in many diseases including diabetic nephropathy. It is acknowledged that oxidative stress plays a critical role in autophagy dysfunction and diabetic nephropathy, and KCa3.1 blockade ameliorates diabetic renal fibrosis through inhibiting TGF-β1 signaling...

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Detalles Bibliográficos
Autores principales: Huang, Chunling, Lin, Mike Z., Cheng, Delfine, Braet, Filip, Pollock, Carol A., Chen, Xin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814925/
https://www.ncbi.nlm.nih.gov/pubmed/27029904
http://dx.doi.org/10.1038/srep23884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814925/
https://www.ncbi.nlm.nih.gov/pubmed/27029904
http://dx.doi.org/10.1038/srep23884

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