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Death receptor 6 (DR6) is required for mouse B16 tumor angiogenesis via the NF-κB, P38 MAPK and STAT3 pathways

Although death receptor 6 (DR6) is aberrantly expressed in certain cancer cell lines, its function, signaling pathway and potential clinical significance in tumor progression are not well characterized. We report here that knocking down DR6 in the mouse B16 cell line has no effect on B16 cell death...

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Detalles Bibliográficos
Autores principales: Yang, X, Shi, B, Li, L, Xu, Z, Ge, Y, Shi, J, Liu, Y, Zheng, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815052/
https://www.ncbi.nlm.nih.gov/pubmed/26950598
http://dx.doi.org/10.1038/oncsis.2016.9