Cargando…

Stress-induced endocytosis and degradation of epidermal growth factor receptor are two independent processes

BACKGROUND: Epidermal growth factor receptor (EGFR) is an important oncogenic protein in multiple types of cancer. Endocytosis and degradation of epidermal growth factor receptor (EGFR) are two key steps for down-regulation of cell surface level of EGFR and modulation of EGFR signaling. Stress condi...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Ke, Dai, Qian, Wei, Jing, Shao, Genbao, Sun, Aiqin, Yang, Wannian, Lin, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815059/
https://www.ncbi.nlm.nih.gov/pubmed/27034618
http://dx.doi.org/10.1186/s12935-016-0301-x