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Stress-induced endocytosis and degradation of epidermal growth factor receptor are two independent processes
BACKGROUND: Epidermal growth factor receptor (EGFR) is an important oncogenic protein in multiple types of cancer. Endocytosis and degradation of epidermal growth factor receptor (EGFR) are two key steps for down-regulation of cell surface level of EGFR and modulation of EGFR signaling. Stress condi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815059/ https://www.ncbi.nlm.nih.gov/pubmed/27034618 http://dx.doi.org/10.1186/s12935-016-0301-x |