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An evolutionary roadmap to the microtubule-associated protein MAP Tau

BACKGROUND: The microtubule associated protein Tau (MAPT) promotes assembly and interaction of microtubules with the cytoskeleton, impinging on axonal transport and synaptic plasticity. Its neuronal expression and intrinsic disorder implicate it in some 30 tauopathies such as Alzheimer’s disease and...

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Detalles Bibliográficos
Autores principales: Sündermann, Frederik, Fernandez, Maria-Pilar, Morgan, Reginald O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815063/
https://www.ncbi.nlm.nih.gov/pubmed/27030133
http://dx.doi.org/10.1186/s12864-016-2590-9