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Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

BACKGROUND: Membrane proteins are key components in a large spectrum of diverse functions and thus account for the major proportion of the drug-targeted portion of the genome. From a structural perspective, the α-helical transmembrane proteins can be categorized into major groups based on the number...

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Detalles Bibliográficos
Autores principales: Attwood, Misty M., Krishnan, Arunkumar, Pivotti, Valentina, Yazdi, Samira, Almén, Markus Sällman, Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815072/
https://www.ncbi.nlm.nih.gov/pubmed/27030248
http://dx.doi.org/10.1186/s12864-016-2592-7