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Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome
BACKGROUND: Membrane proteins are key components in a large spectrum of diverse functions and thus account for the major proportion of the drug-targeted portion of the genome. From a structural perspective, the α-helical transmembrane proteins can be categorized into major groups based on the number...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815072/ https://www.ncbi.nlm.nih.gov/pubmed/27030248 http://dx.doi.org/10.1186/s12864-016-2592-7 |