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Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole
BACKGROUND: Imipramine, a tricyclic antidepressant widely used clinically, has other pharmacological effects, such as antileishmanial activity. Tricyclic antidepressants interact with lipid bilayers, and some studies have shown that imipramine inhibits methyltransferases. Leishmania spp. produces co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815111/ https://www.ncbi.nlm.nih.gov/pubmed/27036654 http://dx.doi.org/10.1186/s13071-016-1467-8 |