Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells

BACKGROUND: Ursolic acid (UA), a natural pentacyclic triterpenoid, exerts anti-tumor effects in various cancer types including hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying this remain largely unknown. METHODS: Cell viability and cell cycle were examined by MTT and Flo...

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Detalles Bibliográficos
Autores principales: Yang, Li Jun, Tang, Qing, Wu, Jingjing, Chen, Yuqing, Zheng, Fang, Dai, Zhenhui, Hann, Swei Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815122/
https://www.ncbi.nlm.nih.gov/pubmed/27036874
http://dx.doi.org/10.1186/s13046-016-0330-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815122/
https://www.ncbi.nlm.nih.gov/pubmed/27036874
http://dx.doi.org/10.1186/s13046-016-0330-2

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