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Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells

BACKGROUND: Ursolic acid (UA), a natural pentacyclic triterpenoid, exerts anti-tumor effects in various cancer types including hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying this remain largely unknown. METHODS: Cell viability and cell cycle were examined by MTT and Flo...

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Detalles Bibliográficos
Autores principales:	Yang, Li Jun, Tang, Qing, Wu, Jingjing, Chen, Yuqing, Zheng, Fang, Dai, Zhenhui, Hann, Swei Sunny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815122/ https://www.ncbi.nlm.nih.gov/pubmed/27036874 http://dx.doi.org/10.1186/s13046-016-0330-2

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