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Sustained delivery of siRNA/PEI complex from in situ forming hydrogels potently inhibits the proliferation of gastric cancer

BACKGROUND: Gastric cancer remains a major cause of mortality and morbidity worldwide. In recent years, gene-based therapeutic strategies were confirmed promising in cancer inhibition and attracted great attention. RNA interference (RNAi) is a powerful tool for gene therapy and has been widely emplo...

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Detalles Bibliográficos
Autores principales: Peng, Hao, Yang, Huawei, Song, Liwei, Zhou, Zheng, Sun, Jinwen, Du, Yunfeng, Lu, Keyu, Li, Tao, Yin, Aiguo, Xu, Jianhua, Wei, Shidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815129/
https://www.ncbi.nlm.nih.gov/pubmed/27029190
http://dx.doi.org/10.1186/s13046-016-0334-y