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Sample size calculation while controlling false discovery rate for differential expression analysis with RNA-sequencing experiments
BACKGROUND: RNA-Sequencing (RNA-seq) experiments have been popularly applied to transcriptome studies in recent years. Such experiments are still relatively costly. As a result, RNA-seq experiments often employ a small number of replicates. Power analysis and sample size calculation are challenging...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815167/ https://www.ncbi.nlm.nih.gov/pubmed/27029470 http://dx.doi.org/10.1186/s12859-016-0994-9 |