NMR analysis of the interaction of picornaviral proteinases Lb and 2A with their substrate eukaryotic initiation factor 4GII

Messenger RNA is recruited to the eukaryotic ribosome by a complex including the eukaryotic initiation factor (eIF) 4E (the cap‐binding protein), the scaffold protein eIF4G and the RNA helicase eIF4A. To shut‐off host–cell protein synthesis, eIF4G is cleaved during picornaviral infection by a virall...

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Detalles Bibliográficos
Autores principales: Aumayr, Martina, Fedosyuk, Sofiya, Ruzicska, Katharina, Sousa‐Blin, Carla, Kontaxis, Georg, Skern, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815241/
https://www.ncbi.nlm.nih.gov/pubmed/26384734
http://dx.doi.org/10.1002/pro.2807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815241/
https://www.ncbi.nlm.nih.gov/pubmed/26384734
http://dx.doi.org/10.1002/pro.2807

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