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Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus
BACKGROUND: Proton irradiation poses a potential hazard to astronauts during and following a mission, with post-mitotic cells at most risk because they cannot dilute resultant epigenetic changes via cell division. Persistent epigenetic changes that result from environmental exposures include gains o...
Autores principales: | Impey, Soren, Pelz, Carl, Tafessu, Amanuel, Marzulla, Tessa, Turker, Mitchell S., Raber, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815246/ https://www.ncbi.nlm.nih.gov/pubmed/27036964 http://dx.doi.org/10.1186/s12864-016-2581-x |
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