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Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease

BACKGROUND: The IL23/Th17 pathway is essential for the onset of inflammatory bowel disease (IBD), yet the specific mechanism by which this pathway initiates the disease remains unknown. In this study, we identify the mechanisms that mediate cross-talk between the IL23 pathway and the intestinal barr...

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Detalles Bibliográficos
Autores principales: Wang, Huiling, Chao, Kang, Ng, Siew Chien, Bai, Alfa Hc, Yu, Qiao, Yu, Jun, Li, Manying, Cui, Yi, Chen, Minhu, Hu, Ji-Fan, Zhang, Shenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815271/
https://www.ncbi.nlm.nih.gov/pubmed/27029486
http://dx.doi.org/10.1186/s13059-016-0901-8