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Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases

Telomeres, the protective ends of linear chromosomes, shorten throughout an individual’s lifetime. Telomere shortening is a hallmark of molecular aging and is associated with premature appearance of diseases associated with aging. Here, we discuss the role of telomere shortening as a direct cause fo...

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Detalles Bibliográficos
Autores principales: Bär, Christian, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815611/
https://www.ncbi.nlm.nih.gov/pubmed/27081482
http://dx.doi.org/10.12688/f1000research.7020.1