Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma

BACKGROUND: Melanoma is a disease that primarily arises in the skin but is a derivative of the neural crest. Eukaryotic translation initiation factor 4E (eIF4E) regulates translation of multiple malignancy-associated mRNAs and is overexpressed in many epithelial tumours. However, expression in human...

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Detalles Bibliográficos
Autores principales: Carter, Julia H, Deddens, James A, Spaulding IV, Nelson Reed, Lucas, Denise, Colligan, Bruce M, Lewis, Thomas Grant, Hawkins, Elyse, Jones, Jordan, Pemberton, Jackson O, Douglass, Larry E, Graff, Jeremy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815768/
https://www.ncbi.nlm.nih.gov/pubmed/26882068
http://dx.doi.org/10.1038/bjc.2015.450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815768/
https://www.ncbi.nlm.nih.gov/pubmed/26882068
http://dx.doi.org/10.1038/bjc.2015.450

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