Loss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis

BACKGROUND: Osteosarcoma (OS) is the most common bone malignancy in the paediatric population, principally affecting adolescents and young adults. Minimal advancements in patient prognosis have been made over the past two decades because of the poor understanding of disease biology. Runx2, a critica...

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Detalles Bibliográficos
Autores principales: Roos, Alison, Satterfield, Laura, Zhao, Shuying, Fuja, Daniel, Shuck, Ryan, Hicks, M John, Donehower, Lawrence A, Yustein, Jason T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815801/
https://www.ncbi.nlm.nih.gov/pubmed/26528706
http://dx.doi.org/10.1038/bjc.2015.305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815801/
https://www.ncbi.nlm.nih.gov/pubmed/26528706
http://dx.doi.org/10.1038/bjc.2015.305

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