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Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis

BACKGROUND: Loss of CDH1 (E-cadherin) expression in cancer cells may promote cell migration and invasion. Therefore, we hypothesised that loss of CDH1 expression in colorectal carcinoma might be associated with aggressive features and clinical outcome. METHODS: Utilising molecular pathological epide...

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Detalles Bibliográficos
Autores principales: Kim, Sun A, Inamura, Kentaro, Yamauchi, Mai, Nishihara, Reiko, Mima, Kosuke, Sukawa, Yasutaka, Li, Tingting, Yasunari, Mika, Morikawa, Teppei, Fitzgerald, Kathryn C, Fuchs, Charles S, Wu, Kana, Chan, Andrew T, Zhang, Xuehong, Ogino, Shuji, Qian, Zhi Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815802/
https://www.ncbi.nlm.nih.gov/pubmed/26742007
http://dx.doi.org/10.1038/bjc.2015.347