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Tumour-infiltrating lymphocyte scores effectively stratify outcomes over and above p16 post chemo-radiotherapy in anal cancer

BACKGROUND: The majority (90%) of anal cancers are human papillomavirus (HPV)-driven, identified using immunochemistry for p16. Compared with HPV− patients, those with HPV+ disease generally show improved survival, although relapse rates around 25% indicate a need for further stratification of this...

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Detalles Bibliográficos
Autores principales: Gilbert, Duncan C, Serup-Hansen, Eva, Linnemann, Dorte, Høgdall, Estrid, Bailey, Charles, Summers, Jeff, Havsteen, Hanne, Thomas, Gareth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815814/
https://www.ncbi.nlm.nih.gov/pubmed/26730577
http://dx.doi.org/10.1038/bjc.2015.448