Cargando…

NF-κB pathway controls mitochondrial dynamics

The Optic atrophy 1 protein (OPA1) is a key element in the dynamics and morphology of mitochondria. We demonstrated that the absence of IκB kinase-α, which is a key element of the nonclassical NF-κB pathway, has an impact on the mitochondrial network morphology and OPA1 expression. In contrast, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Laforge, M, Rodrigues, V, Silvestre, R, Gautier, C, Weil, R, Corti, O, Estaquier, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815975/
https://www.ncbi.nlm.nih.gov/pubmed/26024391
http://dx.doi.org/10.1038/cdd.2015.42