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NF-κB pathway controls mitochondrial dynamics
The Optic atrophy 1 protein (OPA1) is a key element in the dynamics and morphology of mitochondria. We demonstrated that the absence of IκB kinase-α, which is a key element of the nonclassical NF-κB pathway, has an impact on the mitochondrial network morphology and OPA1 expression. In contrast, the...
Autores principales: | Laforge, M, Rodrigues, V, Silvestre, R, Gautier, C, Weil, R, Corti, O, Estaquier, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815975/ https://www.ncbi.nlm.nih.gov/pubmed/26024391 http://dx.doi.org/10.1038/cdd.2015.42 |
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