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The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland

After cessation of lactation, involution of the mouse mammary gland proceeds in two distinct phases, a reversible and an irreversible one, which leads to the death and removal of alveolar cells. Cell death is preceded by the loss of STAT5 activity, which abrogates cell differentiation and gain of ST...

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Detalles Bibliográficos
Autores principales: Schuler, F, Baumgartner, F, Klepsch, V, Chamson, M, Müller-Holzner, E, Watson, C J, Oh, S, Hennighausen, L, Tymoszuk, P, Doppler, W, Villunger, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815977/
https://www.ncbi.nlm.nih.gov/pubmed/26045049
http://dx.doi.org/10.1038/cdd.2015.61