Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling

The activation of cancer-associated fibroblasts (CAFs) is a key event in tumor progression, and alternative extracellular matrix (ECM) proteins derived from CAFs induce ECM remodeling and cancer cell invasion. Here we found that miR-200 s, which are generally downregulated in activated CAFs in breas...

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Detalles Bibliográficos
Autores principales: Tang, X, Hou, Y, Yang, G, Wang, X, Tang, S, Du, Y-E, Yang, L, Yu, T, Zhang, H, Zhou, M, Wen, S, Xu, L, Liu, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815985/
https://www.ncbi.nlm.nih.gov/pubmed/26068592
http://dx.doi.org/10.1038/cdd.2015.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815985/
https://www.ncbi.nlm.nih.gov/pubmed/26068592
http://dx.doi.org/10.1038/cdd.2015.78

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