MYB controls erythroid versus megakaryocyte lineage fate decision through the miR-486-3p-mediated downregulation of MAF

The transcription factor MYB has a key role in hematopoietic progenitor cells (HPCs) lineage choice, by enhancing erythropoiesis at the expense of megakaryopoiesis. We previously demonstrated that MYB controls erythroid versus megakaryocyte lineage decision by transactivating KLF1 and LMO2 expressio...

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Detalles Bibliográficos
Autores principales: Bianchi, E, Bulgarelli, J, Ruberti, S, Rontauroli, S, Sacchi, G, Norfo, R, Pennucci, V, Zini, R, Salati, S, Prudente, Z, Ferrari, S, Manfredini, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816102/
https://www.ncbi.nlm.nih.gov/pubmed/25857263
http://dx.doi.org/10.1038/cdd.2015.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816102/
https://www.ncbi.nlm.nih.gov/pubmed/25857263
http://dx.doi.org/10.1038/cdd.2015.30

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