HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth

HEDGEHOG (HH) signaling is a key regulator of tissue development and its aberrant activation is involved in several cancer types, including melanoma. We and others have shown a reciprocal cross talk between HH signaling and p53, whose function is often impaired in melanoma. Here we present evidence...

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Detalles Bibliográficos
Autores principales: Pandolfi, S, Montagnani, V, Lapucci, A, Stecca, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816112/
https://www.ncbi.nlm.nih.gov/pubmed/26024388
http://dx.doi.org/10.1038/cdd.2015.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816112/
https://www.ncbi.nlm.nih.gov/pubmed/26024388
http://dx.doi.org/10.1038/cdd.2015.56

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