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HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth
HEDGEHOG (HH) signaling is a key regulator of tissue development and its aberrant activation is involved in several cancer types, including melanoma. We and others have shown a reciprocal cross talk between HH signaling and p53, whose function is often impaired in melanoma. Here we present evidence...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816112/ https://www.ncbi.nlm.nih.gov/pubmed/26024388 http://dx.doi.org/10.1038/cdd.2015.56 |