In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases

How metastases develop is not well understood and no genetic mutations have been reported as specific metastatic drivers. Here we have addressed the idea that epigenetic reprogramming by GLI-regulated pluripotent stemness factors promotes metastases. Using primary human colon cancer cells engrafted...

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Detalles Bibliográficos
Autores principales: Singovski, Grigori, Bernal, Carolina, Kuciak, Monika, Siegl-Cachedenier, Irene, Conod, Arwen, Ruiz i Altaba, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816146/
https://www.ncbi.nlm.nih.gov/pubmed/26031752
http://dx.doi.org/10.1093/jmcb/mjv034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816146/
https://www.ncbi.nlm.nih.gov/pubmed/26031752
http://dx.doi.org/10.1093/jmcb/mjv034

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