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In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases
How metastases develop is not well understood and no genetic mutations have been reported as specific metastatic drivers. Here we have addressed the idea that epigenetic reprogramming by GLI-regulated pluripotent stemness factors promotes metastases. Using primary human colon cancer cells engrafted...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816146/ https://www.ncbi.nlm.nih.gov/pubmed/26031752 http://dx.doi.org/10.1093/jmcb/mjv034 |